Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | COMT | P21964 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924233 | 0.82 | SMN1; SMN2 (0.56) | RAB9AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL23758255 | 0.82 | KMT2A (0.60) | KMT2ARAB9AMAPTNPC1GAA | |
| SCHEMBL31680514 | 0.81 | MEN1 (0.51) | KMT2ARAB9ANPC1MEN1TP53 | |
| Hydrochloric Acid SCHEMBL31679089 | 0.81 | KMT2A (0.59) | KMT2ARAB9AMAPTNPC1GAA | |
| SCHEMBL1759307 | 0.80 | KMO (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5613044 | 0.79 | KMT2A (0.57) | KMT2ARAB9AMAPTNPC1GAA | |
| SCHEMBL12647571 | 0.79 | MAP4K4 (0.49) | KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1502412 | 0.79 | KMO (0.51) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL20227586 | 0.78 | KCNK3 (0.79) | KMT2ARAB9ANPC1KCNK3KCNK9 | |
| SCHEMBL10953295 | 0.77 | KDM4E (0.55) | RAB9AMAPTNPC1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403302-B1 | DOUBLE HELICAL NUCLEIC ACID COMPRISING COMPLEMENTARY STRANDS AND OLIGONUCLEOTIDE BOUND TO TARGET SEQUENCE WITHIN; GENETIC ENGINEERING; DIAGNOSING GENE DISORDERS; ANTIPARALLEL ORIENTATION; NON-DENATURING | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-06-11 | — | — | US | disclosed |