Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 7/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729552 | 0.88 | L3MBTL1 (0.41) | L3MBTL1ELANEPLCG1HTTRAB9A | |
| SCHEMBL7729823 | 0.87 | ELANE (0.36) | L3MBTL1ELANEPLCG1HTTRAB9A | |
| SCHEMBL7729933 | 0.86 | L3MBTL1 (0.40) | L3MBTL1ELANEPLCG1HTTRAB9A | |
| SCHEMBL7722386 | 0.85 | L3MBTL1 (0.40) | L3MBTL1ELANEPLCG1HTTRAB9A | |
| SCHEMBL7722604 | 0.83 | PLCG1 (0.36) | L3MBTL1ELANEPLCG1HTTPOLB | |
| SCHEMBL7728199 | 0.83 | L3MBTL1 (0.39) | L3MBTL1ELANEPLCG1HTTRAB9A | |
| SCHEMBL7722528 | 0.82 | L3MBTL1 (0.38) | L3MBTL1ELANEPLCG1HTTRAB9A | |
| SCHEMBL7729704 | 0.82 | L3MBTL1 (0.38) | L3MBTL1ELANEPLCG1HTTRAB9A | |
| SCHEMBL7729400 | 0.82 | L3MBTL1 (0.38) | L3MBTL1ELANEPLCG1HTTRAB9A | |
| SCHEMBL6892390 | 0.81 | CACNA1C (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458780-B1 | IMIDAZO(5,1-B)THIAZOLE GROUP AT THE 2-POSITION ON THE CARBAPENEM RING HAVE HIGH ANTI-MICROBIAL ACTIVITIES AGAINST .BETA.-LACTAMASE PRODUCING BACTERIA, MRSA, RESISTANT-PSEUDOMONAS AERUGINOSA, PRSP, ENTEROCOCCI, AND | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-01 | — | — | US | disclosed |
| EP-1101766-A1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-05-23 | — | — | EP | disclosed |