SCHEMBL7728665

SCHEMBL7728665

C=CCC1CCC(c2cccc(F)c2)CC1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 1/20 0.39
KDM1A O60341 1/20 0.39
RCOR1 Q9UKL0 1/20 0.39
GRM2 Q14416 2/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
HTR2B P41595 1/20 0.39
HCRTR2 O43614 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CHRM4 P08173 1/20 0.35
BPTF Q12830 1/20 0.35
MLYCD O95822 1/20 0.35
PARP10 Q53GL7 1/20 0.35
CCR5 P51681 1/20 0.35
HDAC4 P56524 1/20 0.34
SCD5 Q86SK9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9482504 1.00 DRD4 (0.39) DRD4KDM1ARCOR1GRM2HTR2A
SCHEMBL10409809 0.96 DRD4 (0.37) DRD4KDM1ARCOR1GRM2HTR2A
SCHEMBL10409807 0.96 DRD4 (0.37) DRD4KDM1ARCOR1GRM2HTR2A
SCHEMBL13586235 0.84 CHRM4 (0.38) DRD4KDM1ARCOR1GRM2HTR2A
SCHEMBL29004660 0.83 GRM2 (0.34) GRM2HCRTR2CYP3A4
SCHEMBL2863491 0.82 HTR2C (0.38) DRD4KDM1ARCOR1HTR2AHTR2C
SCHEMBL2863492 0.82 HTR2C (0.38) DRD4KDM1ARCOR1HTR2AHTR2C
SCHEMBL5252309 0.81 DRD2 (0.42) DRD4KDM1ARCOR1HTR2AHTR2C
SCHEMBL1515236 0.81 HTR2C (0.47) DRD4KDM1ARCOR1HTR2AHTR2C
SCHEMBL29878889 0.81 HTR2C (0.47) DRD4KDM1ARCOR1HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6468606-B1 LOW VISCOSITY, HIGH DIELECTRIC ANISOTROPY, LOW OPTICAL ANISOTROPY, EXCELLENT LOW TEMPERATURE COMPATIBILITY WITH OTHER LIQUID CRYSTALLINE COMPOUNDS; 3,4,5-TRIFLUOROPHENYL-(2-FLUORO-4-(TRANS-4-PROPYLCYCLOHEXYL))BENZOATE CHISSO CORPORATION (JP) 2002-10-22 US disclosed
EP-0808825-B1 PHENYL BENZOATE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CHISSO CORP (JP) 2001-09-12 EP disclosed
US-5922243-A LOW VISCOSITY, HIGH DIELECTRIC AND LOW OPTICAL ANISOTROPY, EXCELLENT COMPATIBILITY CHISSO CORPORATION (JP) 1999-07-13 US disclosed
EP-0808825-A1 PHENYL BENZOATE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CHISSO CORPORATION (JP) 1997-11-26 EP disclosed
US-RE34264-E Low viscosity, low temperature compatibility CHISSO CORPORATION (JP) 1993-05-25 US disclosed
EP-0255700-B1 A TOLAN DERIVATIVE AND A LIQUID CRYSTAL MIXTURE CONTAINING THE SAME Chisso Corporation (JP) 1991-10-02 EP disclosed
US-4778620-A Tolan derivative and a liquid crystal mixture containing the same CHISSO CORPORATION (JP) 1988-10-18 US disclosed
EP-0255700-A2 A tolan derivative and a liquid crystal mixture containing the same Chisso Corporation (JP) 1988-02-10 EP disclosed