Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731983 | 0.93 | PLCG1 (0.34) | ALDH1A1PLCG1ELANEHTR2A | |
| SCHEMBL7731024 | 0.90 | PLCG1 (0.35) | PLCG1ELANEHTR2A | |
| SCHEMBL7722374 | 0.89 | PLCG1 (0.35) | PLCG1ELANEHTR2A | |
| SCHEMBL7728742 | 0.89 | PLCG1 (0.35) | ALDH1A1PLCG1ELANEHTR2A | |
| SCHEMBL7728957 | 0.89 | PLCG1 (0.37) | PLCG1ELANEHTR2A | |
| SCHEMBL7728180 | 0.89 | PLCG1 (0.32) | PLCG1 | |
| SCHEMBL7630879 | 0.89 | PLCG1 (0.34) | ALDH1A1PLCG1ELANEHTR2A | |
| SCHEMBL7728647 | 0.89 | ELANE (0.36) | PLCG1ELANEHTR2A | |
| SCHEMBL7730458 | 0.89 | PLCG1 (0.35) | ALDH1A1PLCG1ELANEHTR2A | |
| SCHEMBL7722446 | 0.89 | ELANE (0.36) | PLCG1ELANEHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458780-B1 | IMIDAZO(5,1-B)THIAZOLE GROUP AT THE 2-POSITION ON THE CARBAPENEM RING HAVE HIGH ANTI-MICROBIAL ACTIVITIES AGAINST .BETA.-LACTAMASE PRODUCING BACTERIA, MRSA, RESISTANT-PSEUDOMONAS AERUGINOSA, PRSP, ENTEROCOCCI, AND | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-01 | — | — | US | disclosed |