Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 14/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603515 | 0.89 | MCHR1 (0.49) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL6602805 | 0.89 | MCHR1 (0.62) | POLBMCHR1HTR2CSLC2A1 | |
| SCHEMBL6604858 | 0.87 | MCHR1 (0.53) | POLBMAPTMCHR1HTR2CSLC2A1 | |
| SCHEMBL6602551 | 0.84 | MCHR1 (0.54) | MAPTMCHR1HTR2CGAASMN1; SMN2 | |
| SCHEMBL6605510 | 0.82 | MCHR1 (0.67) | ALDH1A1MAPTMCHR1HTR2CGAA | |
| SCHEMBL6603148 | 0.82 | MCHR1 (0.65) | ALDH1A1MAPTMCHR1HTR2CSMN1; SMN2 | |
| SCHEMBL6602916 | 0.81 | MCHR1 (0.73) | MCHR1HTR2C | |
| SCHEMBL6925443 | 0.78 | MCHR1 (0.81) | MCHR1HTR2CSLC2A1 | |
| SCHEMBL6603526 | 0.78 | MAPT (0.44) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL6603893 | 0.78 | MCHR1 (0.61) | ALDH1A1POLBMAPTHPGDMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399656-B1 | USING A BENZOPYRAN-3-CARBOXAMIDE COMPOUND | SMITHKLINE BEECHAM CORPORATION | 2002-06-04 | — | — | US | disclosed |