Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11162297 | 0.93 | CES2 (0.64) | KMT2ACES2MEN1FAAHMAPK1 | |
| SCHEMBL1604484 | 0.93 | CES2 (0.64) | KMT2ACES2MEN1FAAHMAPK1 | |
| SCHEMBL8773299 | 0.93 | CES2 (0.64) | KMT2ACES2MEN1FAAHMAPK1 | |
| SCHEMBL23950236 | 0.93 | CES2 (0.64) | KMT2ACES2MEN1FAAHMAPK1 | |
| SCHEMBL827134 | 0.93 | CES2 (0.64) | KMT2ACES2MEN1FAAHMAPK1 | |
| SCHEMBL23950441 | 0.93 | CES2 (0.64) | KMT2ACES2MEN1FAAHMAPK1 | |
| SCHEMBL23950237 | 0.93 | CES2 (0.64) | KMT2ACES2MEN1FAAHMAPK1 | |
| SCHEMBL23950131 | 0.93 | CES2 (0.64) | KMT2ACES2MEN1FAAHMAPK1 | |
| SCHEMBL21448801 | 0.93 | CES2 (0.64) | KMT2ACES2MEN1FAAHMAPK1 | |
| SCHEMBL14477972 | 0.93 | CES2 (0.64) | KMT2ACES2MEN1FAAHMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015479-A4 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | LILLY CO ELI (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-1015479-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046631-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |