Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 6/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733173 | 0.99 | FFAR1 (0.37) | FFAR1CYP2C9KCNH2CACNA1CCACNA1H | |
| SCHEMBL7731641 | 0.92 | CACNA1H (0.36) | FFAR1CYP2C9KCNH2CACNA1CCACNA1H | |
| SCHEMBL7731626 | 0.92 | CYP17A1 (0.36) | FFAR1CYP2C9KCNH2CACNA1CCACNA1H | |
| SCHEMBL7732920 | 0.90 | FFAR1 (0.36) | FFAR1CYP2C9KCNH2CACNA1CCACNA1H | |
| SCHEMBL7729274 | 0.89 | FFAR1 (0.36) | FFAR1CYP2C9KCNH2CACNA1CCACNA1H | |
| SCHEMBL7730764 | 0.88 | S1PR1 (0.38) | FFAR1CYP2C9KCNH2CACNA1CCACNA1H | |
| SCHEMBL7722798 | 0.87 | S1PR1 (0.37) | FFAR1CYP2C9KCNH2CACNA1CCACNA1H | |
| SCHEMBL7730786 | 0.87 | HTR2A (0.35) | FFAR1CYP2C9KCNH2CACNA1CCACNA1H | |
| SCHEMBL7730306 | 0.86 | SLC7A5 (0.39) | CACNA1HPDE2AALDH1A1SLC7A5 | |
| SCHEMBL7733355 | 0.86 | PDE2A (0.34) | FFAR1CYP2C9KCNH2CACNA1CPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-5858270-A | Difluorooxymethane derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |