Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731988 | 0.97 | PDE2A (0.33) | PDE2AFFAR1CYP2C9KCNH2CACNA1C | |
| SCHEMBL7731464 | 0.91 | PPARD (0.33) | PDE2ATSHRHCRTR1HCRTR2FFAR1 | |
| SCHEMBL7729451 | 0.91 | FFAR4 (0.34) | PDE2ATSHRHCRTR1HCRTR2 | |
| SCHEMBL7734806 | 0.91 | PDE2A (0.31) | PDE2AEPHX1FFAR1 | |
| SCHEMBL7729328 | 0.90 | PDE2A (0.32) | PDE2A | |
| SCHEMBL7731273 | 0.90 | CETP (0.34) | PDE2AFFAR1CYP2C9KCNH2CACNA1C | |
| SCHEMBL7730361 | 0.88 | CETP (0.36) | PDE2A | |
| SCHEMBL7733206 | 0.87 | CETP (0.33) | — | |
| SCHEMBL7733173 | 0.87 | FFAR1 (0.37) | PDE2ATSHRHCRTR1HCRTR2FFAR1 | |
| SCHEMBL7722822 | 0.87 | HTR2A (0.35) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |