SCHEMBL7729622

SCHEMBL7729622

CCCc1ccc(C(F)(F)Oc2ccc(-c3cc(F)c(F)c(F)c3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.37
PPARG P37231 1/20 0.36
PPARD Q03181 1/20 0.36
PPARA Q07869 1/20 0.36
RARB P10826 3/20 0.35
RARA P10276 2/20 0.35
RARG P13631 1/20 0.35
ANPEP P15144 2/20 0.34
ACACB O00763 1/20 0.33
ACACA Q13085 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
PKM P14618 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14226547 1.00 MAOB (0.37) MAOBPPARGPPARDPPARARARB
SCHEMBL14226543 0.95 MAOB (0.37) MAOBPPARGPPARDPPARARARB
SCHEMBL14226545 0.95 MAOB (0.37) MAOBPPARGPPARDPPARARARB
SCHEMBL17368029 0.92 MAOB (0.36) MAOBPPARGPPARDPPARARARB
SCHEMBL15339479 0.92 MAOB (0.39) MAOBRARBRARARARGACACB
SCHEMBL7731652 0.91 MAOB (0.39) MAOBPPARGPPARDPPARARARB
SCHEMBL7733542 0.91 MAOB (0.35) MAOBPPARDPPARASENP8SENP7
SCHEMBL18719622 0.90 MAOB (0.34) MAOBRARBRARARARGRXRA
SCHEMBL17365909 0.90 S1PR1 (0.34) MAOBRARBRARARARGSENP8
SCHEMBL14226542 0.90 KIF11 (0.38) MAOBRARBRARARARGMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed