Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.58 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737670 | 0.86 | PTGIR (0.55) | PTGIRCYSLTR2CYSLTR1TBXA2RHTR1A | |
| SCHEMBL7737194 | 0.85 | PTGIR (0.56) | PTGIRCYSLTR2CYSLTR1TBXA2RPTGDR2 | |
| SCHEMBL7736944 | 0.84 | PTGIR (0.60) | PTGIRCYSLTR2CYSLTR1SLC6A4 | |
| SCHEMBL7737108 | 0.84 | PTGIR (0.57) | PTGIRCYSLTR2CYSLTR1TBXA2RPTGDR2 | |
| SCHEMBL7737347 | 0.84 | PTGIR (0.57) | PTGIRCYSLTR2CYSLTR1TBXA2RPTGDR2 | |
| SCHEMBL7736507 | 0.83 | PTGIR (0.63) | PTGIRCYSLTR2CYSLTR1HTR1ASLC6A4 | |
| SCHEMBL7736531 | 0.83 | PTGIR (0.56) | PTGIRCYSLTR2CYSLTR1TBXA2RPTGDR2 | |
| SCHEMBL7729962 | 0.82 | PTGIR (0.65) | PTGIRCYSLTR2CYSLTR1HTR1ASLC6A4 | |
| SCHEMBL7736503 | 0.82 | PTGIR (0.55) | PTGIRCYSLTR2CYSLTR1TBXA2RHTR1A | |
| SCHEMBL7736584 | 0.82 | PTGIR (0.64) | PTGIRCYSLTR2CYSLTR1HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |