Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737347 | 0.94 | PTGIR (0.57) | PTGIRTBXA2RCYSLTR2CYSLTR1PTGDR2 | |
| SCHEMBL7737456 | 0.89 | PTGIR (0.51) | PTGIRTBXA2RCYSLTR2CYSLTR1PTGDR2 | |
| SCHEMBL7729950 | 0.86 | PTGIR (0.58) | PTGIRTBXA2RCYSLTR2CYSLTR1HTR1A | |
| SCHEMBL7737194 | 0.83 | PTGIR (0.56) | PTGIRTBXA2RCYSLTR2CYSLTR1PTGDR2 | |
| SCHEMBL7737206 | 0.82 | PTGIR (0.48) | PTGIRTBXA2RALDH1A1 | |
| SCHEMBL7736944 | 0.81 | PTGIR (0.60) | PTGIRCYSLTR2CYSLTR1SLC6A4 | |
| SCHEMBL7739724 | 0.81 | PTGIR (0.54) | PTGIRTBXA2RCYSLTR2CYSLTR1HTR1A | |
| SCHEMBL7737108 | 0.80 | PTGIR (0.57) | PTGIRTBXA2RCYSLTR2CYSLTR1PTGDR2 | |
| SCHEMBL7736507 | 0.80 | PTGIR (0.63) | PTGIRCYSLTR2CYSLTR1HTR1ASLC6A4 | |
| SCHEMBL7737250 | 0.80 | PTGIR (0.46) | PTGIRTBXA2RPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |