Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7731809 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL7735279 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL7723175 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL7722848 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL7733539 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL7723318 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL7733901 | 0.72 | KDM4E (0.31) | — | |
| Hydrochloric Acid SCHEMBL7733617 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL6902595 | 0.69 | CCR1 (0.43) | CCR1CCR5CCR8HDAC6 | |
| SCHEMBL6900082 | 0.66 | CCR1 (0.43) | CCR1CCR5CCR8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458982-B1 | CATALYST SYSTEM COMPRISING AT LEAST ONE METALLOCENE AND AT LEAST ONE COCATALYST. ON SUPPORT. | TARGOR GMBH (DE) | 2002-10-01 | — | — | US | disclosed |