SCHEMBL7730618

SCHEMBL7730618

CCCCCc1cc(F)c(C(F)(F)Oc2ccc(-c3cc(F)c(OC(F)(F)F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.39
RARA P10276 2/20 0.39
RARG P13631 1/20 0.39
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
FFAR4 Q5NUL3 3/20 0.34
SCN9A Q15858 1/20 0.33
PTGS2 P35354 1/20 0.33
PRMT6 Q96LA8 1/20 0.33
FFAR1 O14842 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PPARA Q07869 2/20 0.32
PPARG P37231 1/20 0.32
THRB P10828 1/20 0.32
S1PR1 P21453 1/20 0.31
HDAC3 O15379 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7732787 0.97 FFAR4 (0.35) RARBRARARARGFFAR4SCN9A
SCHEMBL12624827 0.95 RARB (0.44) RARBRARARARGCASP3SENP8
SCHEMBL7728916 0.92 FFAR4 (0.36) RARBRARAFFAR4PRMT6FFAR1
SCHEMBL12624833 0.91 RARB (0.41) RARBRARARARGCASP3SENP8
SCHEMBL12624828 0.91 RARB (0.39) RARBRARARARGCASP3SENP8
SCHEMBL7729601 0.91 THRB (0.38) RARBRARARARGFFAR4PTGS2
SCHEMBL7722828 0.91 RARB (0.41) RARBRARARARGCASP3SENP8
SCHEMBL18746772 0.90 RARB (0.33) RARBRARARARGFFAR4TSHR
SCHEMBL12624832 0.90 RARB (0.42) RARBRARARARGCASP3SENP8
SCHEMBL12623804 0.90 RARB (0.42) RARBRARARARGCASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed