Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731540 | 0.97 | S1PR1 (0.32) | S1PR1PPARGPPARAFFAR1 | |
| SCHEMBL7730606 | 0.93 | S1PR1 (0.35) | S1PR1PPARGPPARATHRBFAAH | |
| SCHEMBL7722652 | 0.92 | FFAR1 (0.32) | FFAR1 | |
| SCHEMBL7730380 | 0.91 | S1PR1 (0.35) | S1PR1PPARGPPARATHRBPLK1 | |
| SCHEMBL14226611 | 0.91 | S1PR1 (0.34) | S1PR1PPARGPPARATHRBFAAH | |
| SCHEMBL7722573 | 0.91 | THRB (0.39) | PPARGPPARATHRBPLK1FAAH | |
| SCHEMBL7733198 | 0.90 | THRB (0.37) | S1PR1PPARGPPARATHRBFAAH | |
| SCHEMBL7734812 | 0.90 | DAO (0.34) | S1PR1PPARGPPARAFFAR1 | |
| SCHEMBL7722731 | 0.89 | RARB (0.41) | S1PR1PPARGPPARATHRBRARB | |
| SCHEMBL7730819 | 0.89 | THRB (0.33) | S1PR1PPARGPPARATHRBPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479646-B1 | Metallocene compounds having indenyl ligand and catalysts for olefin polymerization containing the same | CHISSO CORPORATION (JP) | 2002-11-12 | — | — | US | disclosed |
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |