Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730604 | 1.00 | PPARG (0.39) | PPARGPPARALMNAPOLBTSHR | |
| SCHEMBL7730388 | 0.96 | DAO (0.40) | PPARGPPARALMNAPOLBTSHR | |
| SCHEMBL7735170 | 0.88 | TSHR (0.44) | PPARGPPARALMNATSHREPHX2 | |
| SCHEMBL14749515 | 0.88 | TSHR (0.44) | PPARGPPARALMNATSHREPHX2 | |
| SCHEMBL7732775 | 0.88 | PPARG (0.40) | PPARGPPARALMNAPOLBMAPK1 | |
| SCHEMBL7731001 | 0.88 | PPARG (0.40) | PPARGPPARALMNAPOLBMAPK1 | |
| SCHEMBL7729751 | 0.87 | DAO (0.40) | PPARGPPARALMNAPOLBMAPK1 | |
| SCHEMBL7730399 | 0.85 | PPARA (0.38) | PPARALMNAPOLBMAPK1ALDH1A1 | |
| SCHEMBL7733320 | 0.85 | PPARA (0.38) | PPARALMNAPOLBMAPK1ALDH1A1 | |
| SCHEMBL7730268 | 0.85 | TSHR (0.49) | PPARGPPARALMNATSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |