Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 5/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731047 | 1.00 | HCRTR2 (0.37) | HCRTR2NPY5RGRM2PTGIROPRL1 | |
| SCHEMBL7731038 | 1.00 | HCRTR2 (0.37) | HCRTR2NPY5RGRM2PTGIROPRL1 | |
| SCHEMBL7732668 | 0.83 | ALOX5 (0.33) | HCRTR2 | |
| SCHEMBL7732660 | 0.83 | ALOX5 (0.33) | HCRTR2 | |
| SCHEMBL7732656 | 0.83 | ALOX5 (0.33) | HCRTR2 | |
| SCHEMBL8455912 | 0.81 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL8455913 | 0.81 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL8455909 | 0.81 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL7733904 | 0.80 | OPRL1 (0.30) | OPRL1 | |
| SCHEMBL7733908 | 0.80 | OPRL1 (0.30) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372153-B1 | HIGHER DIELECTRIC ANISOTROPY, EXCELLENT IN MISCIBILITY WITH OTHER LIQUID CRYSTALLINE COMPOUNDS, LOW VISCOSITY, STABLE CHEMICALLY AND PHYSICALLY | CHISSO CORPORATION (JP) | 2002-04-16 | — | — | US | disclosed |
| EP-1020423-A1 | FLUOROALKOXYBENZENE DERIVATIVES HAVING ETHER BOND, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 2000-07-19 | — | — | EP | disclosed |