Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL23R | Q5VWK5 | 13/20 | 0.66 |
| ▸ | KISS1R | Q969F8 | 7/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738071 | 1.00 | IL23R (0.66) | IL23RKISS1R | |
| SCHEMBL12508017 | 1.00 | IL23R (0.66) | IL23RKISS1R | |
| SCHEMBL13248747 | 0.96 | IL23R (0.66) | IL23RKISS1R | |
| SCHEMBL12417333 | 0.96 | IL23R (0.66) | IL23RKISS1R | |
| SCHEMBL12508010 | 0.96 | IL23R (0.66) | IL23RKISS1R | |
| SCHEMBL14498043 | 0.96 | IL23R (0.60) | IL23RKISS1R | |
| SCHEMBL14498050 | 0.95 | IL23R (0.64) | IL23RKISS1R | |
| SCHEMBL12417309 | 0.95 | IL23R (0.64) | IL23RKISS1R | |
| SCHEMBL29403216 | 0.95 | IL23R (0.66) | IL23RKISS1R | |
| SCHEMBL12417315 | 0.94 | KISS1R (0.65) | IL23RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299023-B2 | Neuropeptide-2 receptor (Y-2R) agonists | HOFFMANN-LA ROCHE INC. (US) | 2012-10-30 | — | — | US | disclosed |
| US-8299023-B2 | Neuropeptide-2 receptor (Y-2R) agonists | HOFFMANN-LA ROCHE INC. (US) | 2012-10-30 | — | — | US | disclosed |
| US-8268784-B2 | Neuropeptide-2 receptor (Y-2R) agonists and uses thereof | HOFFMANN-LA ROCHE INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-8268784-B2 | Neuropeptide-2 receptor (Y-2R) agonists and uses thereof | HOFFMANN-LA ROCHE INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20100179093-A1 | Neoropeptide-2-Receptor (Y-2R) Agonists | DANHO WALEED | 2010-07-15 | — | — | US | disclosed |
| US-20100179093-A1 | Neoropeptide-2-Receptor (Y-2R) Agonists | DANHO WALEED | 2010-07-15 | — | — | US | disclosed |
| US-20100137223-A1 | NEUROPEPTIDE-2 RECEPTOR (Y-2R) AGONISTS AND USES THEREOF | CONDE-KNAPE KARIN | 2010-06-03 | — | — | US | disclosed |
| US-20100137223-A1 | NEUROPEPTIDE-2 RECEPTOR (Y-2R) AGONISTS AND USES THEREOF | CONDE-KNAPE KARIN | 2010-06-03 | — | — | US | disclosed |
| US-20100069307-A1 | NEUROPEPTIDE-2 RECEPTOR (Y-2R) AGONISTS | DANHO WALEED | 2010-03-18 | — | — | US | disclosed |
| US-20100069307-A1 | NEUROPEPTIDE-2 RECEPTOR (Y-2R) AGONISTS | DANHO WALEED | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069307-A1 | NEUROPEPTIDE-2 RECEPTOR (Y-2R) AGONISTS | NPY2R, NPY1R, NPY4R | IL23R 438/4885KISS1R 78/4885 |
| US-20100137223-A1 | NEUROPEPTIDE-2 RECEPTOR (Y-2R) AGONISTS AND USES THEREOF | NPY2R, NPY1R, NPY5R | IL23R 428/4885KISS1R 225/4885 |
| US-20100179093-A1 | Neoropeptide-2-Receptor (Y-2R) Agonists | NPY2R, NPY1R, NPY4R | IL23R 392/4885KISS1R 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.