SCHEMBL7732099

SCHEMBL7732099

CCCCCCCCCC(C(=O)Oc1ccccc1)C(=O)Oc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.55
ZDHHC2 Q9UIJ5 1/20 0.49
FAAH O00519 6/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
ALDH1A1 P00352 2/20 0.47
CNR2 P34972 1/20 0.47
TSHR P16473 1/20 0.45
LMNA P02545 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7734011 1.00 TDP1 (0.55) TDP1ZDHHC2FAAHPRSS1PRSS2
SCHEMBL28003821 0.98 TDP1 (0.56) TDP1ZDHHC2FAAHPRSS1PRSS2
SCHEMBL7865921 0.95 TDP1 (0.50) TDP1ZDHHC2FAAHPRSS1PRSS2
SCHEMBL7857923 0.95 TDP1 (0.50) TDP1ZDHHC2FAAHPRSS1PRSS2
SCHEMBL19105264 0.93 TDP1 (0.58) TDP1ZDHHC2FAAHALDH1A1CNR2
SCHEMBL28665494 0.91 TDP1 (0.57) TDP1FAAHALDH1A1TSHRLMNA
SCHEMBL11652057 0.90 TDP1 (0.56) TDP1PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL27359972 0.89 TDP1 (0.53) TDP1ZDHHC2FAAHALDH1A1CNR2
SCHEMBL29163411 0.87 ZDHHC2 (0.49) ZDHHC2FAAHPRSS1PRSS2PRSS3
SCHEMBL3929624 0.87 ZDHHC2 (0.49) ZDHHC2FAAHPRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399738-B1 OXIDATIVE CARBONYLATION OF AROMATIC HYDROXY COMPOUND WITH CARBON MONOXIDE AND OXYGEN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-06-04 US disclosed
US-6300459-B1 TRANSESTERIFYING AROMATIC POLYCARBONATE AND ACTIVE-HYDROGEN COMPOUND UNDER REDUCED PRESSURE FOLLOWED BY REACTION WITH SPECIFIED SALICYLIC ESTER DERIVATIVE TEIJIN LIMITED (JP) 2001-10-09 US disclosed
CN-1072236-C Aromatic polycarbonate composition GE PLASTICS JAPAN LTD (JP) 2001-10-03 CN disclosed
EP-0982340-A1 PROCESS FOR PRODUCING AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-01 EP disclosed
CN-1161346-A Aromatic polycarbonate composition GE PLASTICS JAPAN LTD (JP) 1997-10-08 CN disclosed
CN-1035618-C Process for producing aromatic polycarbonate GE PLASTICS JAPAN LTD (JP) 1997-08-13 CN disclosed
EP-0435124-B1 Processes for preparing aromatic polycarbonates GE PLASTICS JAPAN LTD (JP) 1997-04-02 EP disclosed
US-5606007-A COMPOSITION CONTAINING AROMATIC POLYCARBONATE AND ACID COMPOUND WHICH NEUTRALIZES ALKALINE CATALYST RESIDUES; IMPROVED STABILITY GENERAL ELECTRIC COMPANY (US) 1997-02-25 US disclosed
CN-1053246-A Process for producing aromatic polycarbonate GE PLASTICS JAPAN LTD (JP) 1991-07-24 CN disclosed
EP-0435124-A2 Processes for preparing aromatic polycarbonates GE PLASTICS JAPAN LIMITED (JP) 1991-07-03 EP disclosed