Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 16/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732190 | 0.80 | HTR2A (0.49) | SLC6A4SLC6A2HTR2A | |
| Trifluoroacetic Acid SCHEMBL7723309 | 0.78 | TACR1 (0.46) | SLC6A4SLC6A2SLC6A3TACR1 | |
| SCHEMBL4164384 | 0.75 | MEN1 (0.56) | SLC6A4SLC6A2SLC6A3TACR1HTR2A | |
| Trifluoroacetic Acid SCHEMBL18428991 | 0.71 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3TACR1 | |
| Trifluoroacetic Acid SCHEMBL5671633 | 0.70 | OPRL1 (0.49) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3556747 | 0.70 | MEN1 (0.56) | SLC6A4SLC6A2SLC6A3TACR1 | |
| SCHEMBL4027887 | 0.70 | L3MBTL1 (0.57) | SLC6A4SLC6A2SLC6A3HTR2A | |
| Fumaric Acid SCHEMBL5997414 | 0.69 | SLC6A2 (0.77) | SLC6A4SLC6A2SLC6A3 | |
| Fumaric Acid SCHEMBL5997410 | 0.69 | SLC6A2 (0.77) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL16276728 | 0.68 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399619-B1 | PREVENTION AND TREATMENT OF AIDS AND VIRAL INFECTION BY HIV | MERCK & CO., INC. | 2002-06-04 | — | — | US | disclosed |