Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 7/20 | 0.50 |
| ▸ | FAAH | O00519 | 9/20 | 0.48 |
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732346 | 0.82 | FAAH (0.42) | DAGLAFAAHCES1HSD17B10NPC1 | |
| SCHEMBL7561710 | 0.82 | FAAH (0.42) | DAGLAFAAHCES1HSD17B10NPC1 | |
| SCHEMBL6462278 | 0.82 | FAAH (0.42) | DAGLAFAAHCES1HSD17B10NPC1 | |
| SCHEMBL5431040 | 0.82 | FAAH (0.42) | DAGLAFAAHCES1HSD17B10NPC1 | |
| SCHEMBL5460197 | 0.81 | FAAH (0.44) | DAGLAFAAHCES1HSD17B10NPC1 | |
| SCHEMBL3616775 | 0.81 | FAAH (0.44) | DAGLAFAAHCES1HSD17B10NPC1 | |
| SCHEMBL3616777 | 0.81 | FAAH (0.44) | DAGLAFAAHCES1HSD17B10NPC1 | |
| Hydrochloric Acid SCHEMBL6701346 | 0.80 | FAAH (0.43) | DAGLAFAAHCES1HSD17B10NPC1 | |
| SCHEMBL3960844 | 0.79 | FAAH (0.59) | DAGLAFAAHCES1 | |
| SCHEMBL3962611 | 0.79 | FAAH (0.59) | DAGLAFAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |