SCHEMBL7732318

SCHEMBL7732318

[CH2]c1ccc2c(c1)OCCOCCOCCOCCO2

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.59
LMNA P02545 4/20 0.59
HTT P42858 2/20 0.59
BLM P54132 2/20 0.59
KDM4E B2RXH2 3/20 0.57
GAA P10253 2/20 0.57
SMN1; SMN2 Q16637 3/20 0.54
CRHBP P24387 2/20 0.54
CRHR2 Q13324 2/20 0.54
KMT2A Q03164 1/20 0.47
NPSR1 Q6W5P4 1/20 0.46
POLB P06746 1/20 0.45
RECQL P46063 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ITGB2 P05107 1/20 0.42
ICAM1 P05362 1/20 0.42
ITGAL P20701 1/20 0.42
TSHR P16473 1/20 0.41
ALOX5 P09917 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL360107 0.93 LMNA (0.48) MAPTLMNAHTTBLMKDM4E
SCHEMBL97600 0.84 NPC1 (0.44) MAPTLMNAHTTBLMKDM4E
SCHEMBL2413 0.79 CYP3A4 (0.54) MAPTLMNAKDM4EGAASMN1; SMN2
Hydrochloric Acid SCHEMBL27435892 0.77 CYP3A4 (0.52) MAPTLMNAKDM4EGAASMN1; SMN2
SCHEMBL14696834 0.77 CYP3A4 (0.52) MAPTLMNAKDM4EGAASMN1; SMN2
SCHEMBL15982613 0.75 LMNA (0.60) MAPTLMNAHTTBLMKDM4E
SCHEMBL15982312 0.75 LMNA (0.60) MAPTLMNAHTTBLMKDM4E
SCHEMBL15982628 0.75 LMNA (0.60) MAPTLMNAHTTBLMKDM4E
SCHEMBL15982304 0.75 LMNA (0.85) MAPTLMNAHTTBLMKDM4E
SCHEMBL24402696 0.74 CYP3A4 (0.65) MAPTLMNAHTTBLMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-3609881-A1 CHEMICAL SENSORS BASED ON CARBON NANOTUBES FUNCTIONALISED BY CONJUGATED POLYMERS FOR ANALYSIS IN AQUEOUS MEDIUM Ecole Polytechnique (FR) 2020-02-19 EP disclosed
US-20020031701-A1 High energy density secondary battery for repeated use KAWAKAMI SOICHIRO (JP) 2002-03-14 US disclosed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP disclosed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP disclosed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed