Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732457 | 1.00 | SCN10A (0.35) | SCN10AGAACHRNB2CHRNA4HTR2B | |
| SCHEMBL7732464 | 0.91 | SCN10A (0.42) | SCN10AGAAMAPTKDM4EPKM | |
| SCHEMBL2067985 | 0.80 | GID4 (0.41) | SCN10ATDP1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL7733339 | 0.80 | GID4 (0.41) | SCN10ATDP1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL7722048 | 0.76 | SMN1; SMN2 (0.42) | TDP1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8150633 | 0.74 | F2 (0.39) | GAAMAPTSMN1; SMN2TSHR | |
| SCHEMBL7735942 | 0.74 | F2 (0.39) | GAAMAPTSMN1; SMN2TSHR | |
| SCHEMBL7730858 | 0.74 | F2 (0.39) | GAAMAPTSMN1; SMN2TSHR | |
| SCHEMBL7732752 | 0.72 | GID4 (0.41) | SCN10AGAAMAPTKDM4EPKM | |
| SCHEMBL11718240 | 0.70 | AOC3 (0.53) | GAAMAPTKDM4EPKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |