Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 4/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733175 | 0.96 | RARB (0.42) | RARBRARARARGKIF11CYP11B1 | |
| SCHEMBL14226660 | 0.95 | RARB (0.39) | RARBRARARARGKIF11CYP11B1 | |
| SCHEMBL7732570 | 0.93 | KIF11 (0.39) | RARBRARARARGKIF11CYP11B1 | |
| SCHEMBL12623708 | 0.92 | RARB (0.47) | RARBRARARARGKIF11CYP11B1 | |
| SCHEMBL7729745 | 0.92 | KIF11 (0.39) | RARBRARARARGKIF11CYP11B1 | |
| SCHEMBL12622965 | 0.90 | RARB (0.43) | RARBRARARARGKIF11CYP11B1 | |
| SCHEMBL7735124 | 0.90 | S1PR1 (0.37) | RARBRARARARGS1PR1S1PR3 | |
| SCHEMBL7729149 | 0.90 | RARB (0.36) | RARBRARARARGKIF11CYP11B1 | |
| SCHEMBL7722692 | 0.89 | SKP2 (0.35) | S1PR1S1PR3PPARGPPARASKP2 | |
| SCHEMBL7722731 | 0.88 | RARB (0.41) | RARBRARARARGKIF11CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |