Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13588355 | 0.94 | AR (0.57) | ARHTTHIF1APOLBMAPT | |
| SCHEMBL13588369 | 0.94 | AR (0.57) | ARHTTHIF1APOLBMAPT | |
| SCHEMBL13588367 | 0.93 | AR (0.58) | ARHTTHIF1APOLBMAPT | |
| SCHEMBL13588353 | 0.93 | AR (0.55) | ARHTTHIF1APOLBMAPT | |
| SCHEMBL6535230 | 0.90 | AR (0.51) | ARHTTHIF1APOLBMAPT | |
| Bicarbonate SCHEMBL7732697 | 0.90 | HTT (0.51) | ARHTTHIF1APOLBMAPT | |
| SCHEMBL22020008 | 0.90 | HTT (0.53) | ARHTTHIF1APOLBMAPT | |
| SCHEMBL20610370 | 0.90 | HTT (0.53) | ARHTTHIF1APOLBMAPT | |
| SCHEMBL15349 | 0.90 | HTT (0.53) | ARHTTHIF1APOLBMAPT | |
| SCHEMBL11967041 | 0.90 | HTT (0.53) | ARHTTHIF1APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407148-B1 | ADHESIVE, CURABLE, OR AUTOPOLYMERIZING SEALANT FOR HARD TISSUE; BONDING STRENGTH; SHRINKAGE, POLYMERIZATION AND DISCOLORATION INHIBITION | 3M ESPE AG (DE) | 2002-06-18 | — | — | US | disclosed |