Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.59 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.55 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.55 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732933 | 0.93 | CCR5 (0.65) | CCR5CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7732939 | 0.93 | CCR5 (0.65) | CCR5CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7732334 | 0.92 | CCR5 (0.57) | CCR5CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7732750 | 0.92 | CCR5 (0.57) | CCR5CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7723185 | 0.91 | CCR5 (0.57) | CCR5CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7723179 | 0.91 | CCR5 (0.57) | CCR5CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7731242 | 0.91 | CCR5 (0.57) | CCR5CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7731246 | 0.91 | CCR5 (0.57) | CCR5CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7732304 | 0.90 | CCR5 (0.55) | CCR5CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7732607 | 0.89 | CCR5 (0.68) | CCR5CACNA1FCACNA1DCACNA1SCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399619-B1 | PREVENTION AND TREATMENT OF AIDS AND VIRAL INFECTION BY HIV | MERCK & CO., INC. | 2002-06-04 | — | — | US | disclosed |