Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733024 | 1.00 | MEN1 (0.39) | MEN1KMT2APOLBHSD17B3CYP19A1 | |
| SCHEMBL7734151 | 0.98 | HSD17B3 (0.40) | MEN1KMT2APOLBHSD17B3KCNH2 | |
| SCHEMBL7733578 | 0.98 | HSD17B3 (0.40) | MEN1KMT2APOLBHSD17B3KCNH2 | |
| SCHEMBL7734498 | 0.98 | HSD17B3 (0.40) | MEN1KMT2APOLBHSD17B3KCNH2 | |
| SCHEMBL7734459 | 0.98 | HSD17B3 (0.40) | MEN1KMT2APOLBHSD17B3KCNH2 | |
| SCHEMBL7733059 | 0.98 | HSD17B3 (0.40) | MEN1KMT2APOLBHSD17B3KCNH2 | |
| SCHEMBL7734183 | 0.98 | HSD17B3 (0.40) | MEN1KMT2APOLBHSD17B3KCNH2 | |
| SCHEMBL7735247 | 0.95 | MEN1 (0.39) | MEN1KMT2APOLBHSD17B3CYP19A1 | |
| SCHEMBL7734413 | 0.95 | MEN1 (0.39) | MEN1KMT2APOLBHSD17B3CYP19A1 | |
| SCHEMBL7735060 | 0.89 | MEN1 (0.38) | MEN1KMT2APOLBHSD17B3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407284-B1 | CONTACTING WITH ENZYME; HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-18 | — | — | US | disclosed |