Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 6/20 | 0.34 |
| ▸ | CDC25B | P30305 | 6/20 | 0.34 |
| ▸ | CDC25C | P30307 | 5/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734459 | 1.00 | HSD17B3 (0.40) | HSD17B3MEN1POLBKMT2AKCNH2 | |
| SCHEMBL7733059 | 1.00 | HSD17B3 (0.40) | HSD17B3MEN1POLBKMT2AKCNH2 | |
| SCHEMBL7733024 | 0.98 | MEN1 (0.39) | HSD17B3MEN1POLBKMT2AKCNH2 | |
| SCHEMBL7735247 | 0.94 | MEN1 (0.39) | HSD17B3MEN1POLBKMT2A | |
| SCHEMBL7734413 | 0.94 | MEN1 (0.39) | HSD17B3MEN1POLBKMT2A | |
| SCHEMBL7737030 | 0.88 | MEN1 (0.38) | HSD17B3MEN1POLBKMT2A | |
| SCHEMBL7734186 | 0.81 | HSD17B1 (0.32) | MEN1POLBKMT2A | |
| SCHEMBL7733030 | 0.81 | HSD17B1 (0.32) | MEN1POLBKMT2A | |
| SCHEMBL1087793 | 0.81 | HSD17B1 (0.32) | MEN1POLBKMT2A | |
| SCHEMBL7733048 | 0.81 | HSD17B1 (0.32) | MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407284-B1 | CONTACTING WITH ENZYME; HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-18 | — | — | US | disclosed |