Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724277 | 1.00 | NPC1 (0.43) | NPC1RAB9ATDP1ALDH1A1TP53 | |
| SCHEMBL7735212 | 1.00 | NPC1 (0.43) | NPC1RAB9ATDP1ALDH1A1TP53 | |
| SCHEMBL7733012 | 1.00 | NPC1 (0.43) | NPC1RAB9ATDP1ALDH1A1TP53 | |
| SCHEMBL7733015 | 1.00 | NPC1 (0.43) | NPC1RAB9ATDP1ALDH1A1TP53 | |
| SCHEMBL7735221 | 1.00 | NPC1 (0.43) | NPC1RAB9ATDP1ALDH1A1TP53 | |
| SCHEMBL7734157 | 1.00 | NPC1 (0.43) | NPC1RAB9ATDP1ALDH1A1TP53 | |
| SCHEMBL7737009 | 0.92 | LMNA (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7734192 | 0.92 | LMNA (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7734233 | 0.92 | LMNA (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7733042 | 0.86 | FABP7 (0.54) | NPC1RAB9ATDP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407284-B1 | CONTACTING WITH ENZYME; HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1046712-A2 | Method of resolving 2-oxobicyclo (3.1.0) hexane-6-carboxylic acid derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-25 | — | — | EP | disclosed |