SCHEMBL7733167

SCHEMBL7733167

CCCCCC1CCC(c2ccc(C(F)(F)Oc3cc(F)c(C(F)(F)F)c(F)c3)cc2)CC1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
CYP2C9 P11712 1/20 0.34
SPHK1 Q9NYA1 3/20 0.34
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
HTR2C P28335 2/20 0.32
GAA P10253 1/20 0.31
CNR2 P34972 2/20 0.31
DPP4 P27487 2/20 0.31
ESR2 Q92731 1/20 0.31
IDO1 P14902 1/20 0.31
P2RY14 Q15391 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7733163 1.00 MAPT (0.36) MAPTALDH1A1LMNACYP2C9SPHK1
SCHEMBL7732540 0.97 MAPT (0.34) MAPTALDH1A1LMNACYP2C9SPHK1
SCHEMBL7732551 0.97 MAPT (0.34) MAPTALDH1A1LMNACYP2C9SPHK1
SCHEMBL7732547 0.97 MAPT (0.34) MAPTALDH1A1LMNACYP2C9SPHK1
SCHEMBL7730616 0.97 ALDH1A1 (0.36) MAPTALDH1A1LMNACYP2C9SPHK1
SCHEMBL7730622 0.97 ALDH1A1 (0.36) MAPTALDH1A1LMNACYP2C9SPHK1
SCHEMBL7733213 0.94 ALDH1A1 (0.34) MAPTALDH1A1LMNACYP2C9SPHK1
SCHEMBL7733226 0.94 ALDH1A1 (0.34) MAPTALDH1A1LMNACYP2C9SPHK1
SCHEMBL7733220 0.94 ALDH1A1 (0.34) MAPTALDH1A1LMNACYP2C9SPHK1
SCHEMBL7733221 0.92 ALDH1A1 (0.43) MAPTALDH1A1LMNACYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9605208-B2 Nematic liquid crystal composition DIC CORPORATION (JP) 2017-03-28 US disclosed
US-9321961-B2 Nematic liquid crystal composition DIC Corporation (Tokyo) (JP) 2016-04-26 US disclosed
US-9296949-B2 Nematic liquid crystal composition and liquid crystal display element using the same DIC CORPORATION (JP) 2016-03-29 US disclosed
US-20150284634-A1 NEMATIC LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2015-10-08 US disclosed
US-20150218451-A1 NEMATIC LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2015-08-06 US disclosed
US-20150184076-A1 NEMATIC LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2015-07-02 US disclosed
US-9039929-B2 Nematic liquid crystal composition DIC CORPORATION (JP) 2015-05-26 US disclosed
US-20150060733-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2015-03-05 US disclosed
US-20140225036-A1 NEMATIC LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2014-08-14 US disclosed
EP-2684935-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2014-01-15 EP disclosed
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed
EP-0786508-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY CHISSO CORP (JP) 2001-01-17 EP disclosed
US-5858270-A Difluorooxymethane derivative and liquid crystal composition CHISSO CORPORATION (JP) 1999-01-12 US disclosed
US-5728319-A Liquid crystal composition and liquid crystal display device CHISSO CORPORATION (JP) 1998-03-17 US disclosed
EP-0786508-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY CHISSO CORPORATION (JP) 1997-07-30 EP disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed