SCHEMBL7733206

SCHEMBL7733206

CCCc1ccc(C(F)(F)Oc2cc(F)c(OC(F)F)c(F)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CETP P11597 1/20 0.33
TAAR1 Q96RJ0 1/20 0.30
PSMB5 P28074 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7731273 0.97 CETP (0.34) CETPPSMB5SENP8SENP7SENP6
SCHEMBL7722495 0.93 CETP (0.35) CETP
SCHEMBL7735193 0.91 CETP (0.33) CETPPSMB5SENP8SENP7SENP6
SCHEMBL7730452 0.91 HTR2A (0.36) CETP
SCHEMBL7730361 0.90 CETP (0.36) CETP
SCHEMBL7731988 0.90 PDE2A (0.33)
SCHEMBL7731674 0.89 MAOB (0.33) CETPPSMB5
SCHEMBL7722822 0.89 HTR2A (0.35) CETP
SCHEMBL7731837 0.89 FFAR1 (0.30)
SCHEMBL7731382 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed
US-5858270-A Difluorooxymethane derivative and liquid crystal composition CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed