Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733206 | 0.97 | CETP (0.33) | CETPPSMB5SENP8SENP7SENP6 | |
| SCHEMBL7735193 | 0.94 | CETP (0.33) | CETPPSMB5SENP8SENP7SENP6 | |
| SCHEMBL7730361 | 0.93 | CETP (0.36) | CETPPDE2ADAOPPARGPPARA | |
| SCHEMBL7722822 | 0.92 | HTR2A (0.35) | CETPPPARGPPARATHRBMEN1 | |
| SCHEMBL7731674 | 0.92 | MAOB (0.33) | CETPPSMB5MAOBPPARGPPARA | |
| SCHEMBL7731837 | 0.91 | FFAR1 (0.30) | FFAR1 | |
| SCHEMBL7731382 | 0.91 | — | — | |
| SCHEMBL7722495 | 0.90 | CETP (0.35) | CETPPPARGPPARA | |
| SCHEMBL7733355 | 0.90 | PDE2A (0.34) | PDE2AFFAR1CYP2C9KCNH2CACNA1C | |
| SCHEMBL7730452 | 0.89 | HTR2A (0.36) | CETPPPARGPPARATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |