Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723427 | 0.95 | KMT2A (0.52) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL7732974 | 0.94 | KMT2A (0.51) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL7733006 | 0.91 | TRPV1 (0.56) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL12473704 | 0.86 | KMT2A (0.58) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL1538733 | 0.86 | KMT2A (0.61) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL7734347 | 0.85 | TSHR (0.57) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL1108437 | 0.82 | KMT2A (0.60) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL11863973 | 0.81 | KMT2A (0.56) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL27590316 | 0.81 | KMT2A (0.60) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL81981 | 0.81 | TSHR (0.59) | KMT2AMEN1NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476266-B1 | Diamino compound and production process for the same | CHISSO CORPORATION (JP) | 2002-11-05 | — | — | US | disclosed |