Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695872 | 0.94 | KMT2A (0.57) | KMT2AMEN1RAB9ANPC1TRPV1 | |
| SCHEMBL10936594 | 0.91 | MEN1 (0.63) | KMT2AMEN1RAB9ANPC1TRPV1 | |
| SCHEMBL6989418 | 0.88 | MAPT (0.54) | KMT2AMEN1RAB9ANPC1TRPV1 | |
| SCHEMBL12473704 | 0.84 | KMT2A (0.58) | KMT2AMEN1RAB9ANPC1TRPV1 | |
| SCHEMBL1350599 | 0.84 | MAPT (0.55) | KMT2AMEN1RAB9AALDH1A1TSHR | |
| SCHEMBL1538733 | 0.84 | KMT2A (0.61) | KMT2AMEN1RAB9ANPC1TRPV1 | |
| SCHEMBL9680338 | 0.83 | KMT2A (0.53) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL7733258 | 0.82 | KMT2A (0.56) | KMT2AMEN1RAB9ANPC1TRPV1 | |
| SCHEMBL7734347 | 0.82 | TSHR (0.57) | KMT2AMEN1RAB9ANPC1TRPV1 | |
| SCHEMBL520733 | 0.82 | MEN1 (0.58) | KMT2AMEN1RAB9AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153410-B2 | Alternate morpheein forms of allosteric proteins as a target for the development of bioactive molecules | FOX CHASE CANCER CENTER (US) | 2012-04-10 | — | — | US | disclosed |
| US-20090048324-A1 | ALTERNATE MORPHEEIN FORMS OF ALLOSTERIC PROTEINS AS A TARGET FOR THE DEVELOPMENT OF BIOACTIVE MOLECULES | FOX CHASE CANCER CENTER (US) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048324-A1 | ALTERNATE MORPHEEIN FORMS OF ALLOSTERIC PROTEINS AS A TARGET FOR THE DEVELOPMENT OF BIOACTIVE MOLECULES | BMP2, BMP1, MYOF | KMT2A 4620/4885MEN1 1437/4885RAB9A 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.