SCHEMBL7733299

SCHEMBL7733299

Nc1c(Cl)cc(Cl)c(Cl)c1S(=O)(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 9/20 0.42
CA2 P00918 9/20 0.42
CA9 Q16790 8/20 0.42
CYP2C9 P11712 2/20 0.41
TSHR P16473 5/20 0.38
ALDH1A1 P00352 5/20 0.38
HSD17B10 Q99714 4/20 0.38
CYP3A4 P08684 3/20 0.38
HPGD P15428 3/20 0.38
CASP1 P29466 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
THRB P10828 1/20 0.38
ALOX15 P16050 1/20 0.38
RECQL P46063 1/20 0.38
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CA4 P22748 5/20 0.35
CA12 O43570 4/20 0.34
CA6 P23280 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11654816 0.84 HPGD (0.43) CA1CA2CA9CYP2C9TSHR
SCHEMBL13277953 0.82 HPGD (0.42) CA1CA2CA9CYP2C9TSHR
Hydrochloric Acid SCHEMBL28295347 0.82 HPGD (0.42) CA1CA2CA9CYP2C9TSHR
SCHEMBL6938821 0.77 ALDH1A1 (0.44) CA1CA2CA9TSHRALDH1A1
SCHEMBL11653995 0.76 CYP3A4 (0.46) CA1CA2CA9CYP2C9TSHR
SCHEMBL5436383 0.75 HPGD (0.38) CA1CA2CA9CYP2C9TSHR
SCHEMBL8019424 0.74 CYP2C9 (0.56) CA1CA2CA9CYP2C9TSHR
SCHEMBL8462400 0.72 HPGD (0.33) CYP2C9TSHRHSD17B10CYP3A4HPGD
SCHEMBL8462290 0.72 HPGD (0.33) CYP2C9TSHRHSD17B10CYP3A4HPGD
SCHEMBL342035 0.71 ALDH1A1 (0.52) CA1CA2CA9CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6407220-B1 FOR DYEING AND PRINTING OF MATERIALS CONTAINING CELLULOSE FIBERS; HIGH FIXATION AND GOOD BUILD-UP EVERLIGHT USA, INC. 2002-06-18 US disclosed
EP-0126405-A1 Pyrazolone azo dyestuffs BASF Aktiengesellschaft (DE) 1984-11-28 EP disclosed