Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14226646 | 0.98 | RARB (0.35) | RARBRARARARGPPARGPPARA | |
| SCHEMBL7735200 | 0.96 | RARB (0.41) | RARBRARARARGPPARGPPARA | |
| SCHEMBL7730036 | 0.94 | RARB (0.37) | RARBRARARARGPPARGPPARA | |
| SCHEMBL7732784 | 0.92 | RARB (0.33) | RARBRARARARGPPARGPPARA | |
| SCHEMBL12624703 | 0.91 | RARB (0.46) | RARBRARARARGPPARGPPARA | |
| SCHEMBL12623706 | 0.91 | RARB (0.46) | RARBRARARARGPPARGPPARA | |
| SCHEMBL14226776 | 0.91 | RARB (0.40) | RARBRARARARGPPARGPPARA | |
| SCHEMBL7722828 | 0.90 | RARB (0.41) | RARBRARARARGPPARGPPARA | |
| SCHEMBL21937826 | 0.90 | RARB (0.41) | RARBRARARARGS1PR1S1PR3 | |
| SCHEMBL15965527 | 0.90 | RARB (0.41) | RARBRARARARGS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |