SCHEMBL7732784

SCHEMBL7732784

CCCc1cc(F)c(C(F)(F)Oc2ccc(-c3cc(F)c(F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.33
RARA P10276 2/20 0.33
MAOB P27338 1/20 0.32
ANPEP P15144 4/20 0.32
PRMT6 Q96LA8 1/20 0.32
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30
RARG P13631 1/20 0.30
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
PKM P14618 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7735137 0.93 DAO (0.35) RARBRARAPRMT6PPARGPPARD
SCHEMBL7733314 0.92 RARB (0.36) RARBRARAMAOBPRMT6PPARG
SCHEMBL7735200 0.91 RARB (0.41) RARBRARAPPARGPPARARARG
SCHEMBL14226646 0.90 RARB (0.35) RARBRARAPPARGPPARARARG
SCHEMBL17108380 0.90 RARB (0.35) RARBRARAMAOBRARGNPC1
SCHEMBL503178 0.90 RARB (0.35) RARBRARAMAOBRARGNPC1
SCHEMBL7732941 0.89 PRMT6 (0.35) RARBRARAMAOBANPEPPRMT6
SCHEMBL7734936 0.89 THRB (0.36) MAOBNPC1RAB9ASMN1; SMN2
SCHEMBL7728916 0.89 FFAR4 (0.36) RARBRARAPRMT6PPARDPPARA
SCHEMBL12623683 0.88 S1PR1 (0.35) RARBRARAMAOBRARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed