Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.58 |
| ▸ | CA2 | P00918 | 6/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonamide SCHEMBL17513129 | 1.00 | CA1 (0.58) | CA1CA2CA7CA13EPHX1 | |
| SCHEMBL28036572 | 0.80 | CA1 (0.38) | CA1CA2CA12CA14NPSR1 | |
| Trifluoromethanesulfonamide SCHEMBL28388248 | 0.80 | CA2 (0.69) | CA1CA2CA7CA13EPHX1 | |
| Trifluoromethanesulfonic Acid SCHEMBL27506904 | 0.79 | NPSR1 (0.35) | CA1CA2CA7CA13EPHX1 | |
| SCHEMBL10434526 | 0.79 | CA1 (0.30) | CA1CA2CA7CA13EPHX1 | |
| Trifluoromethanesulfonic Acid SCHEMBL610462 | 0.79 | NPSR1 (0.35) | CA1CA2CA7CA13EPHX1 | |
| SCHEMBL9016120 | 0.78 | CA2 (0.38) | CA1CA2CA7CA13 | |
| Trifluoromethanesulfonamide SCHEMBL9894379 | 0.78 | CA2 (0.65) | CA1CA2CA7CA13EPHX1 | |
| Trifluoromethanesulfonamide SCHEMBL28468956 | 0.77 | CA1 (0.73) | CA1CA2CA7CA13EPHX1 | |
| Trifluoromethanesulfonamide SCHEMBL4437078 | 0.77 | CA1 (0.73) | CA1CA2CA7CA13EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399820-B2 | PLACING A NUCLEOPHILE, WHOSE NUCLEOPHILIC ATOM IS ADVANTAGEOUSLY A NITROGEN, IN CONTACT WITH A SULPHONYL HALIDE AND AN ORGANIC BASE | RHODIA CHIMIE (FR) | 2002-06-04 | — | — | US | disclosed |
| US-20010020113-A1 | Process and reagent useful for the synthesis of sulphanilide which is perhalogenated on the carbon borne by the sulphur atom of the sulphanilide function | DESMURS JEAN-ROGER (FR) | 2001-09-06 | — | — | US | disclosed |
| US-6271419-B1 | Process and reagent useful for the synthesis of sulphanilide which is perhalogenated on the carbon borne by the sulphur atom of the sulphanilide function | RHODIA CHIMIE (FR) | 2001-08-07 | — | — | US | disclosed |