Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733512 | 1.00 | CCR1 (0.42) | CCR1CHRM2CCR5MDM2TP53 | |
| SCHEMBL441836 | 0.85 | CCR1 (0.60) | CCR1CHRM2CCR5MDM2 | |
| SCHEMBL441837 | 0.85 | CCR1 (0.60) | CCR1CHRM2CCR5MDM2 | |
| SCHEMBL5485987 | 0.83 | CCR1 (0.44) | CCR1CHRM2CCR5MDM2TP53 | |
| SCHEMBL6362657 | 0.82 | CCR1 (0.38) | CCR1CHRM2CCR5TP53 | |
| SCHEMBL6363771 | 0.80 | CCR1 (0.35) | CCR1CHRM2CCR5 | |
| SCHEMBL6363775 | 0.80 | CCR1 (0.35) | CCR1CHRM2CCR5 | |
| SCHEMBL1323820 | 0.79 | CCR1 (0.35) | CCR1 | |
| SCHEMBL1323821 | 0.79 | CCR1 (0.35) | CCR1 | |
| SCHEMBL1323469 | 0.79 | CCR1 (0.35) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020169155-A1 | A nitrogen-ring containing triheterocyclic compound is useful for treating a disease associated with aberrant leukocyte recruitment and/or activation | MILLENNIUM PHARMACEUTICALS, INC. | 2002-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169155-A1 | A nitrogen-ring containing triheterocyclic compound is useful for treating a disease associated with aberrant leukocyte recruitment and/or activation | NFATC1, ELANE, NCF1 | CCR1 9/4885CHRM2 2950/4885CCR5 109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.