Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.50 |
| ▸ | CTSS | P25774 | 8/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13707738 | 0.89 | CTSK (0.48) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL8951268 | 0.88 | CTSK (0.48) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL8353044 | 0.87 | CTSK (0.50) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL3226823 | 0.87 | CTSK (0.50) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL7735308 | 0.87 | CTSK (0.47) | CTSKCTSSCA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL9218636 | 0.87 | CTSK (0.47) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL7735263 | 0.87 | CTSK (0.48) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL8281467 | 0.87 | CTSK (0.48) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL7728040 | 0.85 | CTSK (0.49) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL14401962 | 0.85 | CTSK (0.49) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800434-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2004-10-05 | — | — | US | disclosed |