Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734536 | 0.92 | TSHR (0.41) | MAPTSMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7731897 | 0.85 | TDP1 (0.42) | MAPTSMN1; SMN2ALDH1A1LMNANPC1 | |
| SCHEMBL7731880 | 0.83 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2ALDH1A1LMNAMAPK1 | |
| SCHEMBL7734559 | 0.83 | CA1 (0.44) | MAPTSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7733858 | 0.82 | MEN1 (0.43) | MAPTSMN1; SMN2EGFRALDH1A1LMNA | |
| SCHEMBL28799124 | 0.71 | TSHR (0.39) | MAPTALDH1A1MAPK1L3MBTL1NPC1 | |
| SCHEMBL27914437 | 0.68 | KDM4E (0.60) | MAPTSMN1; SMN2EGFRALDH1A1LMNA | |
| Biphenyl SCHEMBL28188851 | 0.68 | SMN1; SMN2 (0.56) | MAPTSMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7995836 | 0.68 | LMNA (0.40) | LMNAMAPK1L3MBTL1HTTHPGD | |
| SCHEMBL14247549 | 0.67 | SRC (0.46) | MAPTSMN1; SMN2ALDH1A1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399787-B1 | TRANSITION METAL COMPLEX | PENN STATE RESEARCH FOUNDATION | 2002-06-04 | — | — | US | disclosed |
| WO-1999059721-A1 | CATALYTIC ASYMMETRIC HYDROGENATION, HYDROFORMYLATION, AND HYDROVINYLATION VIA TRANSITION METAL CATALYSTS WITH PHOSPHINES AND PHOSPHITES | THE PENN STATE RESEARCH FOUNDATION (US) | 1999-11-25 | — | — | WO | disclosed |