SCHEMBL7733714

SCHEMBL7733714

CCOCCNc1ccccc1NCCOCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.45
HTT P42858 2/20 0.45
UTS2R Q9UKP6 1/20 0.43
SMN1; SMN2 Q16637 5/20 0.41
KDM4E B2RXH2 4/20 0.41
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.41
USP2 O75604 1/20 0.41
TP53 P04637 1/20 0.41
NSD2 O96028 1/20 0.41
HSP90AA1 P07900 1/20 0.41
MAPK1 P28482 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
POLB P06746 2/20 0.40
NCF1 P14598 1/20 0.38
HPGD P15428 1/20 0.38
SRC P12931 1/20 0.38
GBA1 P04062 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10408248 0.88 MAPT (0.64) MAPTHTTUTS2RSMN1; SMN2KDM4E
SCHEMBL10498572 0.87 PTGER4 (0.40) MAPTHTTUTS2RSMN1; SMN2KDM4E
SCHEMBL13127890 0.85 MAPT (0.60) MAPTHTTUTS2RSMN1; SMN2KDM4E
SCHEMBL7770772 0.85 CHRM2 (0.57) MAPTSMN1; SMN2RAB9ANPC1MAPK1
SCHEMBL9361414 0.84 UTS2R (0.40) MAPTHTTUTS2RSMN1; SMN2KDM4E
SCHEMBL1420925 0.81 MAPT (0.52) MAPTUTS2RSMN1; SMN2KDM4ERAB9A
SCHEMBL6595723 0.80 MAPT (0.65) MAPTHTTSMN1; SMN2RAB9ANPC1
SCHEMBL28159193 0.79 POLB (0.40) KDM4EHSP90AA1POLBHPGDALDH1A1
SCHEMBL13280252 0.79 KDM4E (0.62) HTTSMN1; SMN2KDM4ETP53NPSR1
SCHEMBL22580957 0.79 UTS2R (0.36) MAPTHTTUTS2RSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399272-B1 Phenylenediamine derivative-type additive useful for a chemically amplified photoresist HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-06-04 US disclosed