Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881553 | 0.91 | CHRM2 (0.62) | CHRM2GAAALDH1A1MAPTRAB9A | |
| SCHEMBL7733714 | 0.85 | MAPT (0.45) | CHRM2ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL7771127 | 0.84 | CHRM2 (0.62) | CHRM2GAAALDH1A1MAPTRAB9A | |
| SCHEMBL1644001 | 0.82 | CHRM2 (0.64) | CHRM2GAAALDH1A1MAPTRAB9A | |
| SCHEMBL6173269 | 0.79 | CHRM2 (0.70) | CHRM2GAAALDH1A1MAPTRAB9A | |
| SCHEMBL10408248 | 0.79 | MAPT (0.64) | GAAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL7772573 | 0.78 | CHRM2 (0.55) | CHRM2ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL30994802 | 0.77 | CHRM2 (0.58) | CHRM2GAAALDH1A1MAPTRAB9A | |
| SCHEMBL1022424 | 0.77 | CHRM2 (0.58) | CHRM2GAAALDH1A1MAPTRAB9A | |
| SCHEMBL11496106 | 0.77 | CHRM2 (0.73) | CHRM2GBA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990643-B1 | Luminescence indicator for determining calcium ions | AVL MEDICAL INSTR (CH) | 2001-07-25 | — | — | EP | disclosed |
| US-6171866-B1 | N-SUBSTITUTED IMINODIACETIC ACID DERIVATIVES | AVL MEDICAL INSTRUMENTS (CH) | 2001-01-09 | — | — | US | disclosed |
| EP-0990643-A1 | Luminescence indicator for determining calcium ions | AVL Medical Instruments (CH) | 2000-04-05 | — | — | EP | disclosed |