Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 9/20 | 0.70 |
| ▸ | GNAI3 | P08754 | 8/20 | 0.61 |
| ▸ | GNAI1 | P63096 | 8/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL31318598 | 0.98 | GNAO1 (0.68) | GNAO1GNAI3GNAI1KCNH2HRH3 | |
| Fluoride SCHEMBL30330791 | 0.98 | GNAO1 (0.68) | GNAO1GNAI3GNAI1KCNH2HRH3 | |
| Fluoride SCHEMBL29251923 | 0.98 | GNAO1 (0.68) | GNAO1GNAI3GNAI1KCNH2HRH3 | |
| Fluoride SCHEMBL29251703 | 0.98 | GNAO1 (0.68) | GNAO1GNAI3GNAI1KCNH2HRH3 | |
| Fluoride SCHEMBL29252068 | 0.98 | GNAO1 (0.68) | GNAO1GNAI3GNAI1KCNH2HRH3 | |
| Fluoride SCHEMBL29252503 | 0.98 | GNAO1 (0.68) | GNAO1GNAI3GNAI1KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL30330734 | 0.98 | GNAO1 (0.73) | GNAO1GNAI3GNAI1KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL30330544 | 0.96 | GNAO1 (0.70) | GNAO1GNAI3GNAI1KCNH2HRH3 | |
| Cyanide SCHEMBL30330128 | 0.94 | GNAO1 (0.64) | GNAO1GNAI3GNAI1KCNH2HRH3 | |
| Cyanide SCHEMBL30330571 | 0.94 | GNAO1 (0.64) | GNAO1GNAI3GNAI1KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239750-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | C4 THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2020132561-A1 | TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2017197055-A1 | HETEROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2017-11-16 | — | — | WO | disclosed |
| WO-2017197051-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2017-11-16 | — | — | WO | disclosed |
| US-7790744-B2 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |