Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878523 | 0.89 | CHRM2 (0.68) | CHRM2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL1644001 | 0.82 | CHRM2 (0.64) | CHRM2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL881553 | 0.81 | CHRM2 (0.62) | CHRM2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL5800488 | 0.81 | CHRM2 (0.62) | CHRM2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7771127 | 0.81 | CHRM2 (0.62) | CHRM2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL3073595 | 0.81 | CHRM2 (0.62) | CHRM2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL4168734 | 0.81 | CHRM2 (0.62) | CHRM2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL10632588 | 0.79 | CHRM2 (0.59) | CHRM2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL12162852 | 0.79 | CHRM2 (0.65) | CHRM2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL6173269 | 0.79 | CHRM2 (0.70) | CHRM2ALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101759665-B | Substituent phenylpiperazine aryl alkanol derivant and application thereof in preparing analgesics | NHWA PHARMACEUTICAL GROUP CO LTD | 2012-03-28 | — | — | CN | disclosed |
| CN-101759665-A | Substituent phenylpiperazine aryl alkanol derivant and application thereof in preparing analgesics | NHWA PHARMACEUTICAL GROUP CO L | 2010-06-30 | — | — | CN | disclosed |
| US-6399614-B1 | TREATING NEUROMUSCULAR DYSFUNCTION OF LOWER URINARY TRACT VIA PERIPHERAL OR CENTRAL NERVOUS SYSTEM; SEROTONIN RECEPTOR ANTAGONIST | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-04 | — | — | US | disclosed |