SCHEMBL3073595

SCHEMBL3073595

COc1ccccc1NCCO

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.62
GBA1 P04062 4/20 0.57
KDM4E B2RXH2 1/20 0.57
GLA P06280 1/20 0.57
TSHR P16473 2/20 0.53
HTT P42858 2/20 0.53
RAD52 P43351 2/20 0.53
USP2 O75604 1/20 0.53
ALDH1A1 P00352 3/20 0.49
HSD17B10 Q99714 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.47
NR1I2 O75469 1/20 0.47
AHR P35869 1/20 0.47
GSK3A P49840 1/20 0.47
GSK3B P49841 1/20 0.47
CDK5 Q00535 1/20 0.47
CDK5R1 Q15078 1/20 0.47
HPGD P15428 1/20 0.46
NPC1 O15118 1/20 0.46
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL4244724 0.92 CHRM2 (0.58) CHRM2GBA1KDM4EGLATSHR
SCHEMBL11109142 0.89 CHRM2 (0.68) CHRM2GBA1KDM4EGLATSHR
SCHEMBL27982786 0.84 TSHR (0.55) CHRM2GBA1KDM4EGLATSHR
SCHEMBL12162852 0.83 CHRM2 (0.65) CHRM2GBA1HTTALDH1A1L3MBTL1
SCHEMBL1644001 0.82 CHRM2 (0.64) CHRM2GBA1HTTALDH1A1L3MBTL1
SCHEMBL2476416 0.82 KDM4E (0.47) CHRM2GBA1KDM4EGLATSHR
SCHEMBL8470228 0.81 ALDH1A1 (0.55) GBA1KDM4EGLATSHRALDH1A1
SCHEMBL7771127 0.81 CHRM2 (0.62) CHRM2KDM4EUSP2ALDH1A1HSD17B10
SCHEMBL4168734 0.81 CHRM2 (0.62) CHRM2ALDH1A1L3MBTL1NPC1GAA
SCHEMBL881553 0.81 CHRM2 (0.62) CHRM2HTTALDH1A1L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006087194-A2 DYE COMPOSITION COMPRISING AN OXONOL TYPE METHINE DIRECT DYE, PROCESS FOR IMPLEMENTATION AND USES THEREOF L'OREAL (FR) 2006-08-24 WO claimed
EP-0591373-B1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD OREAL (FR) 1996-05-22 EP claimed
EP-0467026-B1 HAIR DYEING COMPOSITION AND ITS USE GOLDWELL AKTIENGESELLSCHAFT (DE) 1993-03-03 EP claimed
WO-2025129290-A1 METHODS FOR TREATING KERATIN FIBERS IN A DYEING PROCESS L'OREAL (FR) 2025-06-26 WO disclosed
WO-2024241332-A1 PRODUCT CONTAINING A DYE COMPOSITION COMPRISING A FATTY ACID, A NON-IONIC SURFACTANT, A NON-ASSOCIATIVE POLYMER, AT LEAST 10% BY WEIGHT OF ONE OR MORE FATTY SUBSTANCES, A POLYOL, A SPECIFIC DYE PRECURSOR AND AN OXIDIZING COMPOSITION L'ORÉAL (FR) 2024-11-28 WO disclosed
EP-4395734-A1 COMPOSITIONS, KITS, AND METHODS FOR ALTERING THE COLOR OF HAIR L'OREAL (FR) 2024-07-10 EP disclosed
WO-2024134667-A1 A DEVICE COMPRISING OXIDATIVE COMPOSITION FOR DYEING OF KERATIN FIBRES L'OREAL (FR) 2024-06-27 WO disclosed
WO-2024030362-A1 COMPOSITIONS AND METHODS FOR ALTERING THE COLOR OF HAIR L'OREAL (FR) 2024-02-08 WO disclosed
CN-117069720-A 5-HT 2A Receptor agonist, preparation method and application thereof 上海翊石医药科技有限公司 2023-11-17 CN disclosed
US-11701308-B2 Compositions for coloring hair including ultra-efficient high aqueous, multi-lamellar emulsion systems, and methods of making the same COMBE INCORPORATED (US) 2023-07-18 US disclosed
WO-2023034391-A1 COMPOSITIONS, KITS, AND METHODS FOR ALTERING THE COLOR OF HAIR L'OREAL (FR) 2023-03-09 WO disclosed
WO-2001056538-A1 NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING P&G-CLAIROL, INC. (US) 2001-08-09 WO disclosed
WO-2001009125-A1 NOVEL 8-CARBONYL CHROMAN DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF AVENTIS PHARMA S.A. (FR) 2001-02-08 WO disclosed
EP-0592396-B1 BENZOXAZINE DYES BRISTOL MYERS SQUIBB CO (US) 1997-04-16 EP disclosed
EP-0592396-A1 BENZOXAZINE DYES. BRISTOL MYERS SQUIBB CO (US) 1994-04-20 EP disclosed
EP-0580713-A1 METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR. OREAL (FR) 1994-02-02 EP disclosed
EP-0592396-A4 BENZOXAZINE DYES. BRISTOL MYERS SQUIBB CO (US) 1992-09-28 EP disclosed
US-5118323-A Hair dyes CLAIROL, INC. 1992-06-02 US disclosed
US-5055110-A Hair dyes CLAIROL INCORPORATED (US) 1991-10-08 US disclosed
WO-1991007394-A1 BENZOXAZINE DYES BRISTOL-MYERS SQUIBB COMPANY (US) 1991-05-30 WO disclosed