Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CETP | P11597 | 1/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 9/20 | 0.61 |
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559389 | 0.92 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4ENPSR1HSD17B10 | |
| SCHEMBL28728842 | 0.88 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4ENPSR1HSD17B10 | |
| SCHEMBL11732563 | 0.86 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4ENPSR1HSD17B10 | |
| SCHEMBL7814976 | 0.86 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4ENPSR1HSD17B10 | |
| SCHEMBL15528570 | 0.85 | KDM4E (0.97) | ALDH1A1HPGDKDM4ENPSR1HSD17B10 | |
| SCHEMBL28256535 | 0.85 | CETP (0.77) | ALDH1A1HPGDKDM4ENPSR1HSD17B10 | |
| SCHEMBL12323604 | 0.85 | CETP (0.77) | ALDH1A1HPGDKDM4ENPSR1HSD17B10 | |
| SCHEMBL28258088 | 0.85 | CETP (0.77) | ALDH1A1HPGDKDM4ENPSR1HSD17B10 | |
| SCHEMBL4839328 | 0.84 | SIRT2 (0.75) | ALDH1A1HPGDKDM4ENPSR1HSD17B10 | |
| SCHEMBL11734795 | 0.84 | ALDH1A1 (0.70) | ALDH1A1HPGDKDM4ENPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399614-B1 | TREATING NEUROMUSCULAR DYSFUNCTION OF LOWER URINARY TRACT VIA PERIPHERAL OR CENTRAL NERVOUS SYSTEM; SEROTONIN RECEPTOR ANTAGONIST | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-04 | — | — | US | disclosed |