Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733529 | 1.00 | MMP2 (0.39) | MMP2MMP9ANPEPALDH1A1MEN1 | |
| SCHEMBL7726401 | 1.00 | MMP2 (0.39) | MMP2MMP9ANPEPALDH1A1MEN1 | |
| SCHEMBL7733815 | 1.00 | MMP2 (0.39) | MMP2MMP9ANPEPALDH1A1MEN1 | |
| SCHEMBL7726398 | 1.00 | MMP2 (0.39) | MMP2MMP9ANPEPALDH1A1MEN1 | |
| SCHEMBL7727967 | 0.89 | BTK (0.40) | MMP2MMP9ANPEPALDH1A1MEN1 | |
| SCHEMBL7726096 | 0.89 | BTK (0.40) | MMP2MMP9ANPEPALDH1A1MEN1 | |
| SCHEMBL7728179 | 0.89 | BTK (0.40) | MMP2MMP9ANPEPALDH1A1MEN1 | |
| SCHEMBL7726834 | 0.89 | BTK (0.40) | MMP2MMP9ANPEPALDH1A1MEN1 | |
| SCHEMBL7721954 | 0.89 | BTK (0.40) | MMP2MMP9ANPEPALDH1A1MEN1 | |
| SCHEMBL7721952 | 0.89 | BTK (0.40) | MMP2MMP9ANPEPALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |