Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473637 | 0.95 | PROKR1 (0.45) | PTGDR2S1PR1PROKR1HCRTR2HCRTR1 | |
| SCHEMBL614853 | 0.83 | HTR2C (0.63) | HTR1ASLC6A2SLC6A4HTR2CSLC6A3 | |
| SCHEMBL29691303 | 0.83 | HTR2C (0.63) | HTR1ASLC6A2SLC6A4HTR2CSLC6A3 | |
| Hydrochloric Acid SCHEMBL4890789 | 0.81 | HTR2C (0.64) | HTR1ASLC6A2SLC6A4HTR2CSLC6A3 | |
| SCHEMBL16455098 | 0.81 | HTR2A (0.53) | HTR1DHTR1AHTR2C | |
| SCHEMBL31232347 | 0.81 | PTGDR2 (0.57) | PTGDR2PROKR1HCRTR2HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL16446772 | 0.80 | HTR2A (0.52) | HTR1DHTR1AHTR2C | |
| SCHEMBL2399633 | 0.79 | PTGDR2 (0.57) | PTGDR2HTR1DHTR1BADRA2AHTR1A | |
| SCHEMBL31389943 | 0.79 | PROKR1 (0.39) | PROKR1HCRTR2HCRTR1OPRM1HTR2C | |
| SCHEMBL9956909 | 0.76 | DRD2 (0.62) | PTGDR2HTR1DDRD1DRD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372153-B1 | HIGHER DIELECTRIC ANISOTROPY, EXCELLENT IN MISCIBILITY WITH OTHER LIQUID CRYSTALLINE COMPOUNDS, LOW VISCOSITY, STABLE CHEMICALLY AND PHYSICALLY | CHISSO CORPORATION (JP) | 2002-04-16 | — | — | US | disclosed |