Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.85 |
| ▸ | TSHR | P16473 | 6/20 | 0.85 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.85 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL27775486 | 1.00 | — | — | |
| Acrylamide SCHEMBL28037683 | 0.96 | — | — | |
| Acrylamide SCHEMBL27927662 | 0.96 | — | — | |
| Acrylamide SCHEMBL11342051 | 0.92 | ALDH1A1 (0.85) | ALDH1A1TSHRFGFR4LMNAALOX15 | |
| Acrylamide SCHEMBL943492 | 0.92 | — | — | |
| Acrylamide SCHEMBL10611203 | 0.92 | ALDH1A1 (0.85) | ALDH1A1TSHRFGFR4LMNAALOX15 | |
| Acrylamide SCHEMBL21247467 | 0.92 | — | — | |
| Acrylamide SCHEMBL732729 | 0.92 | ALDH1A1 (0.85) | ALDH1A1TSHRFGFR4LMNAALOX15 | |
| Acrylamide SCHEMBL170034 | 0.92 | TSHR (1.00) | ALDH1A1TSHRFGFR4LMNAALOX15 | |
| Acrylamide SCHEMBL183292 | 0.92 | TSHR (1.00) | ALDH1A1TSHRFGFR4LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413941-B1 | ANTICANCER AGENTS | WEST PHARMACEUTICAL SERVICES DRUG DELIVERY & CLINICAL RESEARCH CENTRE LIMITED (GB) | 2002-07-02 | — | — | US | disclosed |