Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 13/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354087 | 0.93 | PDE4A (0.47) | PDE5APDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6974761 | 0.84 | PDE4A (0.47) | PDE4APDE4BPDE4DPDE4CSSTR5 | |
| SCHEMBL7724896 | 0.84 | PDE4A (0.47) | PDE4APDE4BPDE4DPDE4CSSTR5 | |
| SCHEMBL8325337 | 0.83 | PDE4A (0.48) | PDE4APDE4BPDE4DPDE4CSSTR5 | |
| Hydrochloric Acid SCHEMBL7724907 | 0.83 | PDE4A (0.46) | PDE4APDE4BPDE4DPDE4CSSTR5 | |
| SCHEMBL13350324 | 0.82 | PDE4A (0.46) | PDE4APDE4BPDE4DPDE4CSSTR5 | |
| SCHEMBL8324871 | 0.82 | PDE4A (0.46) | PDE4APDE4BPDE4DPDE4CSSTR5 | |
| SCHEMBL7734051 | 0.76 | PDE4D (0.49) | PDE5APDE4APDE4BPDE4DPDE4C | |
| Hydrochloric Acid SCHEMBL7734781 | 0.76 | PDE4D (0.49) | PDE5APDE4APDE4BPDE4DPDE4C | |
| SCHEMBL6971404 | 0.76 | PDE4D (0.47) | PDE5APDE4APDE4BPDE4DPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | claimed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | claimed |
| US-5665737-A | PHOSPHODIESTERASE INHIBITORS | EURO-CELTIQUE, S.A. (LU) | 1997-09-09 | — | — | US | claimed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | claimed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | claimed |
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| US-5665737-A | PHOSPHODIESTERASE INHIBITORS | EURO-CELTIQUE, S.A. (LU) | 1997-09-09 | — | — | US | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |